Lyrica blue and white capsule
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Pregabalin belongs to the class of medication known as analgesics. It is used to relieve neuropathic pain associated with diabetic peripheral neuropathy pain from damaged nerves due to diabetes and postherpetic neuralgia persisting pain following healing of the rash due to shingles. Pregabalin is also used to relieve pain associated with fibromyalgia pain in the muscles, ligaments, and tendons. It is also useful in managing central neuropathic pain pain from damaged nerves of the brain and spinal cord. Pain from damaged nerves may feel sharp, burning, tingling, shooting, or numb.
Lyrica blue and white capsule
If you are a consumer or patient please visit this version. DPN Pain 2. Fibromyalgia 2. Dose should be adjusted in patients with reduced renal function. Administer the total daily dose in two or three divided doses. In view of dose-dependent adverse reactions and since LYRICA is eliminated primarily by renal excretion, adjust the dose in patients with reduced renal function. Base the dose adjustment in patients with renal impairment on creatinine clearance CLcr , as indicated in Table 1. Then refer to Table 1 to determine the corresponding renal adjusted dose. For patients undergoing hemodialysis, adjust the pregabalin daily dose based on renal function. In addition to the daily dose adjustment, administer a supplemental dose immediately following every 4-hour hemodialysis treatment see Table 1. The oral solution is 20 mg pregabalin per milliliter mL and prescriptions should be written in milligrams mg. The pharmacist will calculate the applicable dose in mL for dispensing e. LYRICA is contraindicated in patients with known hypersensitivity to pregabalin or any of its components. Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy.
Base the dose adjustment in patients with renal impairment on creatinine clearance CLcras indicated in Table 1. In controlled clinical trials, 0.
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If you are a consumer or patient please visit this version. Because LYRICA is eliminated primarily by renal excretion, adjust the dose in adult patients with reduced renal function [see Dosage and Administration 2. The recommended dosages for adults and pediatric patients 1 month of age and older are included in Table 1. Administer the total daily dosage orally in two or three divided doses as indicated in Table 1. In pediatric patients, the recommended dosing regimen is dependent upon body weight. Based on clinical response and tolerability, dosage may be increased, approximately weekly. Patients who do not experience sufficient pain relief after 2 to 3 weeks of treatment with mg two times a day and who tolerate LYRICA may be treated with up to mg two times a day [see Clinical Studies In view of dose-dependent adverse reactions and since LYRICA is eliminated primarily by renal excretion, adjust the dose in adult patients with reduced renal function.
Lyrica blue and white capsule
Lyrica is a brand-name prescription medication. Lyrica is also FDA-approved to treat partial onset seizures in children ages 1 month and older. For this purpose, Lyrica is used with other seizure drugs. Lyrica belongs to a drug class called antiepileptic drugs. A drug class is a group of medications that work in a similar way. Lyrica comes as capsules that you swallow. Lyrica capsules are available in the following strengths:.
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Discontinue pregabalin immediately in these patients. The following adverse reactions have been identified during postapproval use of pregabalin. Patients were allowed to take acetaminophen and nonsteroidal anti-inflammatory drugs during the studies. Seniors may need lower doses of this medication to reduce the possibility for side effects. White to off White color granular powder filled in Size "2" hard gelatin capsules with White Opaque body imprinted "PGBN" and light blue Opaque cap imprinted "" with black ink available in:. Single-dose administration of oxycodone 10 mg had no effect on the steady-state pharmacokinetics of pregabalin. Renal Impairment and Hemodialysis Pregabalin clearance is nearly proportional to creatinine clearance CLcr. It is inactive at serotonin and dopamine receptors and does not inhibit dopamine, serotonin, or noradrenaline reuptake. What should I tell my healthcare provider before taking pregabalin capsules? Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy [see Warnings and Precautions 5. White to off White color granular powder filled in Size "4" hard gelatin capsules with White Opaque body imprinted "PGBN" and light blue Opaque cap imprinted "50" with black ink available in:.
Pregabalin is a prescription drug.
Following is a list of treatment-emergent adverse reactions reported by patients treated with LYRICA during all clinical trials. Pregabalin undergoes negligible metabolism in humans. Concomitant drug has no effect on the pharmacokinetics of pregabalin. Pregabalin mg oral capsule was given every 12 hours mg daily dose for a total of four doses. Talk to your doctor if you are taking these medications. Instruct patients to discontinue pregabalin and immediately seek medical care if they experience these symptoms [ see Warnings and Precautions 5. Phenytoin, carbamazepine, valproic acid, and lamotrigine. Patients taking gabapentin were required to discontinue gabapentin treatment 1 week prior to entering baseline. In preclinical studies in rats, pregabalin was associated with an increased risk of male-mediated teratogenicity. If you take too much pregabalin capsules, call your healthcare provider or poison control center, or go to the nearest emergency room right away. Data A pharmacokinetic study in ten lactating women, who were at least 12 weeks postpartum, evaluated the concentrations of pregabalin in plasma and breast milk. Seniors may need lower doses of this medication to reduce the possibility for side effects.
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