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Tizanidine belongs to a group of medications called muscle relaxants. Tizanidine is used to treat spasticitya condition where muscles in your body spasm, cramp, or become tight due to medical problems such as multiple sclerosis or spine injury, apo ti-4 pill high.
These health issues are also linked to symptoms like muscle rigidity and hypertonia. In these cases, tizanidine hydrochloride is used as a muscle relaxant to mitigate pain. Since it alleviates pain, is tizanidine a narcotic? While narcotics are substances traditionally used to treat pain by binding to receptors in the nervous system — such as opioids - tizanidine is a muscle relaxer. Also known by brand names like Comfort Pac-tizanidine and Zanaflex, tizanidine belongs to a class of drugs called central alphaadrenergic agonists. These drugs work by blocking nerve impulses or pain sensations between the brain and body, specifically pain that occurs around the skeletal muscle areas.
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If you are a consumer or patient please visit this version. Tizanidine is a central alphaadrenergic agonist indicated for the management of spasticity. Because of the short duration of therapeutic effect, treatment with tizanidine should be reserved for those daily activities and times when relief of spasticity is most important. Because of the short duration of therapeutic effect, treatment with tizanidine should be reserved for those daily activities and times when relief of spasticity is most important [see Dosage and Administration 2. Tizanidine tablets may be prescribed with or without food. Once the formulation has been selected and the decision to take with or without food has been made, this regimen should not be altered. Food has complex effects on tizanidine pharmacokinetics, which differ with the different formulations. Tizanidine capsules and tizanidine tablets are bioequivalent to each other under fasting conditions more than 3 hours after a meal , but not under fed conditions within 30 minutes of a meal. These pharmacokinetic differences may result in clinically significant differences when switching administration of tablet and capsules and when switching administration between the fed or fasted state. These changes may result in increased adverse events, or delayed or more rapid onset of activity, depending upon the nature of the switch. For this reason, the prescriber should be thoroughly familiar with the changes in kinetics associated with these different conditions [see Clinical Pharmacology The recommended starting dose is 2 mg. Because the effect of tizanidine peaks at approximately 1 to 2 hours post-dose and dissipates between 3 to 6 hours post-dose, treatment can be repeated at 6 to 8 hour intervals, as needed, to a maximum of three doses in 24 hours. Dosage can be gradually increased by 2 mg to 4 mg at each dose, with 1 to 4 days between dosage increases, until a satisfactory reduction of muscle tone is achieved. The total daily dose should not exceed 36 mg.
The following adverse reactions are described elsewhere in other sections of the prescribing information:, apo ti-4 pill high. Although there have been no clinical studies evaluating the effects of other CYP1A2 inhibitors on tizanidine, other CYP1A2 inhibitors, such as zileuton, other fluoroquinolones, antiarrythmics amiodarone, mexiletine, propafenone and verapamilcimetidine, famotidine oral contraceptives, acyclovir and ticlopidine, may also lead to substantial increases in tizanidine blood concentrations [see Warnings and Precautions 5.
Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine. Tizanidine does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition. Tizanidine acts on the central nervous system CNS to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.
Tizanidine is in a class of drugs called skeletal muscle relaxants. It works by slowing the central nervous system to allow muscles to relax. The U. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Apo ti-4 pill high
Tizanidine belongs to a group of medications called muscle relaxants. Tizanidine is used to treat spasticity , a condition where muscles in your body spasm, cramp, or become tight due to medical problems such as multiple sclerosis or spine injury. Muscle relaxants work by blocking excess firing of the nerve cells that control muscle movement.
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Birth control pills prevent tizanidine from leaving the body readily and may cause tizanidine to build up in the body leading to side effects. Breast-feeding: It is not known if tizanidine passes into breast milk. Drug Label Information Updated December 15, If you are a consumer or patient please visit this version. Follow your doctor's orders or the directions on the label. Two studies were conducted in patients with multiple sclerosis and one in patients with spinal cord injury. Apotex Corp. Advertising Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. How Does Tizanidine Work? Therefore, concomitant use of tizanidine with fluvoxamine or with ciprofloxacin, potent inhibitors of CYP1A2, is contraindicated [see Contraindications 4 and Drug Interactions 7. Take this medicine only as directed by your doctor.
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In these patients, during titration, the individual doses should be reduced. Tizanidine should be used with caution in renally impaired patients [see Warnings and Precautions 5. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These patients should be monitored closely for the onset or increase in severity of the common adverse events dry mouth, somnolence, asthenia and dizziness as indicators of potential overdose [see Dosage and Administration 2. Starting this medication at a very low dose and gradually increasing the daily dose helps to reduce the effect of rapidly dropping blood pressure. If higher doses are required, individual doses rather than dosing frequency should be increased [see Warnings and Precautions 5. Version Files Dec 18, 10 current download Jul 22, 9 download Dec 5, 8 download Jun 2, 7 download Dec 4, 6 download Jan 9, 5 download May 9, 4 download Jul 8, 3 download. However, elderly patients are more likely to have kidney problems, which may require caution in patients receiving this medicine. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Because of the short duration of therapeutic effect, treatment with tizanidine should be reserved for those daily activities and times when relief of spasticity is most important. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. Taking these high doses is also more likely to produce unwanted side effects rather than a high.
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