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This medication is a single formulation containing 2 drugs, sulfamethoxazole and trimethoprim.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
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If you are a consumer or patient please visit this version. To reduce the development of drug-resistant bacteria and maintain the effectiveness of sulfamethoxazole and trimethoprim tablets and other antibacterial drugs, sulfamethoxazole and trimethoprim tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Sulfamethoxazole and trimethoprim is a synthetic antibacterial combination product available in DS double strength tablets, each containing mg sulfamethoxazole and mg trimethoprim; in tablets, each containing mg sulfamethoxazole and 80 mg trimethoprim for oral administration. It is a white to off-white, practically odorless, crystalline powder, tasteless compound with a molecular weight of Trimethoprim is 2,4-diamino 3,4,5-trimethoxybenzyl pyrimidine; the molecular formula is C 14 H 18 N 4 O 3. It is a white or cream-colored crystals or crystalline powder with a molecular weight of Inactive Ingredients: Docusate sodium, magnesium stearate, pregelatinized starch maize , sodium benzoate, and sodium starch glycolate. Sulfamethoxazole and trimethoprim is rapidly absorbed following oral administration. Both sulfamethoxazole and trimethoprim exist in the blood as unbound, protein-bound and metabolized forms; sulfamethoxazole also exists as the conjugated form. Sulfamethoxazole is metabolized in humans to at least 5 metabolites: the N 4 -acetyl-, N 4 -hydroxy-, 5-methylhydroxy-, N 4 -acetylmethylhydroxy-sulfamethoxazole metabolites, and an N-glucuronide conjugate. Trimethoprim is metabolized in vitro to 11 different metabolites, of which, five are glutathione adducts and six are oxidative metabolites, including the major metabolites, 1- and 3-oxides and the 3- and 4-hydroxy derivatives. The free forms of sulfamethoxazole and trimethoprim are considered to be the therapeutically active forms.
Check with your health care professional if any of the following side effects continue or white pill with h49 bothersome or if you have any questions about them:. Life threatening hyperkalemia and acidosis secondary to trimethoprim-sulfamethoxazole treatment. This medicine may cause hypoglycemia low blood sugar in some patients.
If you are a consumer or patient please visit this version. To reduce the development of drug-resistant bacteria and maintain the effectiveness of sulfamethoxazole and trimethoprim tablets and other antibacterial drugs, sulfamethoxazole and trimethoprim tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Sulfamethoxazole and trimethoprim is a synthetic antibacterial combination product available in DS double strength tablets, each containing mg sulfamethoxazole and mg trimethoprim; in tablets, each containing mg sulfamethoxazole and 80 mg trimethoprim for oral administration. It is a white to off-white, practically odorless, crystalline powder, tasteless compound with a molecular weight of Trimethoprim is 2,4-diamino 3,4,5-trimethoxybenzyl pyrimidine; the molecular formula is C 14 H 18 N 4 O 3. It is a white or cream-colored crystals or crystalline powder with a molecular weight of
If you are a consumer or patient please visit this version. Sulfamethoxazole and trimethoprim is a synthetic antibacterial combination product available in DS double strength tablets, each containing mg sulfamethoxazole and mg trimethoprim; in tablets, each containing mg sulfamethoxazole and 80 mg trimethoprim for oral administration. It is a white to off-white, practically odorless, crystalline powder, tasteless compound with a molecular weight of Trimethoprim is 2,4-diamino 3,4,5-trimethoxybenzyl pyrimidine; the molecular formula is C14H18N4O3. It is a white or cream-colored crystals or crystalline powder with a molecular weight of Inactive Ingredients: Docusate sodium, magnesium stearate, pregelatinized starch maize , sodium benzoate, and sodium starch glycolate. Sulfamethoxazole and trimethoprim is rapidly absorbed following oral administration. Both sulfamethoxazole and trimethoprim exist in the blood as unbound, protein-bound and metabolized forms; sulfamethoxazole also exists as the conjugated form. Sulfamethoxazole is metabolized in humans to at least 5 metabolites: the N4-acetyl-, N4-hydroxy-, 5-methylhydroxy-, N4-acetylmethylhydroxy-sulfamethoxazole metabolites, and an N-glucuronide conjugate.
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Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.
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Product Information. It is very important that your doctor check the progress of you or your child at regular visits to make sure that this medicine is working properly. Reprint Permissions A single copy of these materials may be reprinted for noncommercial personal use only. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImage , we no longer display the RxImage pill images associated with drug labels. Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation. An identical daily dosage is used for 5 days in the treatment of shigellosis. Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by binding to and reversibly inhibiting the required enzyme, dihydrofolate reductase. Aerobic gram-negative bacteria Escherichia coli including susceptible enterotoxigenic strains implicated in traveler's diarrhea Klebsiella species Enterobacter species Haemophilus influenzae Morganella morganii Proteus mirabilis Proteus vulgaris Shigella flexneri Shigella sonnei. Clinical studies of sulfamethoxazole and trimethoprim did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. This medicine may cause diarrhea, and in some cases it can be severe. Prevention and treatment of Pneumocystis pneumonia. We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. Error Include a valid email address.
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Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy. Medicines can interact with certain foods. International Patients. Acidification of the urine will increase renal elimination of trimethoprim. Sulfamethoxazole is metabolized in humans to at least 5 metabolites: the N 4 -acetyl-, N 4 -hydroxy-, 5-methylhydroxy-, N 4 -acetylmethylhydroxy-sulfamethoxazole metabolites, and an N-glucuronide conjugate. Impaired Phenylalanine Metabolism The trimethoprim component of sulfamethoxazole and trimethoprim has been noted to impair phenylalanine metabolism, but this is of no significance in phenylketonuric patients on appropriate dietary restriction. It is recommended that initial episodes of uncomplicated urinary tract infections be treated with a single effective antibacterial agent rather than the combination. Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Kaplan SA, et al. Check with your doctor right away if you or your child have a rash, itching, swelling of the face, tongue, and throat, trouble breathing, or chest pain after you use the medicine. Version Files Jul 8, 8 current download Jun 28, 7 download Sep 24, 6 download Oct 3, 5 download Jan 8, 4 download Nov 2, 3 download Apr 11, 2 download Apr 12, 1 download.
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