Sertraline and ibuprofen interaction

If you take the antidepressant Zoloftyou may have noticed that your prescription insert says taking ibuprofen with Zoloft increases your risk of bleeding.

It is very important that your doctor check your or your child's progress at regular visits. This is to allow for changes in your dose and to help reduce any side effects. Blood tests may be needed to check for unwanted effects. Do not start taking sertraline during the 14 days after you stop a MAO inhibitor and wait 14 days after stopping sertraline before you start taking a MAO inhibitor. If you take them together or do not wait 14 days, you may develop confusion, agitation, restlessness, stomach or intestinal symptoms, a sudden high body temperature, an extremely high blood pressure, or severe convulsions. Using these medicines together can cause serious problems. Sertraline may cause a serious condition called serotonin syndrome if taken together with some medicines.

Sertraline and ibuprofen interaction

Sertraline is a selective serotonin reuptake inhibitor SSRI , which is a class of drugs that also includes Prozac and Paxil. SSRIs increase the amount of serotonin in the brain. Serotonin is a neurotransmitter responsible for sending signals between brain cells, in particular, signals associated with positive emotions. The chemical thus is vital to determining your mood and overall emotional state. Sertraline has been on the market since and at first, was sold by Pfizer as Zoloft, but today generic versions are widely available. It is one of the most commonly prescribed antidepressants in the United States and elsewhere. It is prescribed to treat depression, panic attacks, social anxiety, obsessive-compulsive disorder OCD , and post-traumatic stress. In the United States alone there are over 35 million annual prescriptions. Sertraline also is prescribed as a low-dose ad-hoc treatment for premature ejaculation. When taken hours prior to sexual activity it helps with delaying ejaculation, making sex more enjoyable for men who suffer from premature ejaculation. It can also be prescribed as a daily medication for this purpose, and is actually more effective in treating premature ejaculation when taken daily. Yes, headaches are one of the possible side effects of sertraline, but they usually are limited to the first few weeks of treatment. Once sertraline concentrations in your body have stabilized, headaches tend to resolve. Similarly, you may experience headaches after you discontinue sertraline. These headaches also stop occurring after a few weeks.

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Currently viewing BNF. View sertraline drug monograph. Sertraline has the following interaction information:. Severe interactions are highlighted with a red marker. Find out more about BNF interactions information. Both Sertraline and Aceclofenac can increase the risk of hyponatraemia. Acenocoumarol causes bleeding, as can Sertraline ; concurrent use might increase the risk of developing this effect.

There is an interaction between Zoloft sertraline and ibuprofen , but they are sometimes used together safely for short periods of time. Many studies suggest that intermittent use is safe for most but not all people. The issue with combing Zoloft, an SSRI selective serotonin reuptake inhibitor and ibuprofen , an NSAID non-steroidal anti-inflammatory drug , is that taking both for extended periods of time can increase the risk of stomach irritation and bleeding particularly GI bleeds. Be sure to discuss with your doctor the use of ibuprofen before you take it if you are also on Zoloft. Both ibuprofen and Zoloft have antiplatelet effects. Therefore, the use of them together potentiates the blood-thinning effect, increasing the risk of bleeding episodes.

Sertraline and ibuprofen interaction

If you take the antidepressant Zoloft , you may have noticed that your prescription insert says taking ibuprofen with Zoloft increases your risk of bleeding. You may have heard that long-term use of nonsteroidal anti-inflammatory drugs NSAIDs , like ibuprofen, can cause stomach problems like bleeding or ulcers. Adding an antidepressant, such as Zoloft sertraline , ups those chances. But serotonin has another role: It encourages platelets to clump together and form clots.

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Both Sertraline and Tolfenamic acid can increase the risk of hyponatraemia. Both Sertraline and Primidone can cause sedation, which might affect the ability to perform skilled tasks see 'Drugs and Driving' in Guidance on Prescribing. Anxiety Treatment. Sertraline causes bleeding, as can Inotersen ; concurrent use might increase the risk of developing this effect. Both Sertraline and Guanfacine can cause sedation, which might affect the ability to perform skilled tasks see 'Drugs and Driving' in Guidance on Prescribing. Both Sertraline and Lofepramine can cause sedation, which might affect the ability to perform skilled tasks see 'Drugs and Driving' in Guidance on Prescribing. View sertraline drug monograph. It's safe to take ibuprofen with paracetamol or codeine. Both Sertraline and Apomorphine can cause sedation, which might affect the ability to perform skilled tasks see 'Drugs and Driving' in Guidance on Prescribing. Both Dr. Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. Both Sertraline and Lisdexamfetamine can increase the risk of serotonin syndrome. Cautions with other medicines Ibuprofen does not mix well with some medicines. Both Sertraline and Vinorelbine can increase the risk of hyponatraemia.

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Both Sertraline and Risperidone can increase the risk of hyponatraemia. Both Sertraline and Nintedanib can increase the risk of bleeding. Both Sertraline and Cilostazol can increase the risk of bleeding. Both Sertraline and Amisulpride can cause sedation, which might affect the ability to perform skilled tasks see 'Drugs and Driving' in Guidance on Prescribing. Both Sertraline and Tenoxicam can increase the risk of bleeding. Performance Anxiety Propranolol for Anxiety. This is to allow for changes in your dose and to help reduce any side effects. Sharing options Share Icon. PrEP Emtricitabine-tenofovir generic Truvada. Both Sertraline and Chlortalidone can increase the risk of hyponatraemia. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Both Sertraline and Nortriptyline can increase the risk of hyponatraemia. Private and secure. Before taking any other medicines, check the label to see if they contain aspirin, ibuprofen or other NSAIDs. Anxiety Treatment.