Pet scan suv values chart

Most often used in conjunction with CT or MRI, it helps radiologists distinguish between healthy tissue and diseased tissue so that cancer can be accurately diagnosed, correctly staged, and appropriately treated.

Federal government websites often end in. The site is secure. The authors confirm that all data underlying the findings are fully available without restriction. All relevant data are within the paper. Cancer and metabolic bone diseases can alter the SUV. Eleven studies met all the criteria.

Pet scan suv values chart

Federal government websites often end in. The site is secure. Fusion was performed on nodes with reported having metabolic activity. The reference standard was cytology. Below SUV max of 2. The number of metastases, their laterality, the involved node levels and the presence of extracapsular spread are important predictive parameters [ 2 ]. In a systematic review Lodder et al. Elective treatment is not always necessary if the risk of occult metastases is very low. To minimize treatment morbidity, accurate staging is thus very important [ 4 , 5 ]. A systematic review and meta-analysis of elective neck dissection vs active surveillance of cT1-T2N0 squamous cell carcinoma SCC of the oral cavity showed that elective neck dissection END results in fewer regional recurrences than active surveillance [ 6 ]. Still, watchful waiting is considered a treatment option in case of a low risk for metastases and a very close follow-up of the neck [ 7 ].

Several studies have pointed out that there is no such magic cut-off SUV value to label a finding either benign or malignant [4][5].

Cancer Imaging volume 16 , Article number: 35 Cite this article. Metrics details. Interpretation requires integration of the metabolic and anatomic findings provided by the PET and CT components which transcend the knowledge base isolated in the worlds of nuclear medicine and radiology, respectively. This encompasses how we display, threshold intensity of images and sequence our review, which are essential for accurate interpretation. For interpretation, it is important to be aware of benign variants that demonstrate high glycolytic activity, and pathologic lesions which may not be FDG-avid, and understand the physiologic and biochemical basis of these findings. This is a modality with many patterns of structural, physiologic and biochemical abnormalities that transcend the boundaries previously isolated in the worlds of nuclear medicine or radiology in characterising pathological conditions, particularly including cancer. Future articles in this series will address the use of other tracers pertinent to other cancers.

The FDG is distributed throughout the body based on how much uptake there is in the tissues. Higher SUV values means there is more uptake in the tissues. This is reflected in the scan as a hotter or brighter area. The precise definition of SUV is a ratio of radioactivity concentration in tissue at a point in time divided by the injected dose of radioactivity per kilogram of the patients weight. Quite complicated but not crucial to remember for scan interpretation. SUV can change over time because of imaging factors like image noise and how the SUV is measured by the user. The SUV gives us an idea of how hot or active the tissues are compared to the rest of the body. The higher the SUV, the more likely it is abnormal. Some normal tissues like the brain, liver, and spleen have higher SUV values because they take up more FDG then the rest of the body.

Pet scan suv values chart

At the time the article was last revised Liz Silverstone had no financial relationships to ineligible companies to disclose. The concentration of F 18 activity reflects glucose metabolism which is increased in tumor cells and inflammation. SUV is also known as the dose uptake ratio DUR and is a mathematically derived ratio of tissue radioactivity concentration at a point in time C T at a specific region of interest ROI and the injected dose of radioactivity per kilogram of the patient's body weight 7 :. Uptake values are sometimes normalized to lean body mass LBM or body surface area. However body weight is the most commonly used because it is easy to calculate and is reproducible 7. SUV may be influenced by biological and technical factors such as blood glucose level, image noise, image resolution and variable region of interest selection.

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In follicular lymphoma or chronic lymphocytic leukaemia, discordant sites of high metabolic activity can be a specific finding for transformed disease. Being able to help people understand their scan gives them the confidence they deserve to have before going into treatment. At the time the article was created Ki Yap had no recorded disclosures. This corresponds to an upper SUV window threshold of 8—10 and will usually achieve an appropriate contrast, except in very large patients in whom this may make the liver too dark. Figure 2 shows the distribution of SUV max values in a boxplot. Return to Blog Search Statistical evaluation Calculation of sensitivity and specificity of the techniques was not possible as not all patients had a neck dissection with a pathology report. Ann Nucl Med 22 : — FDG PET a demonstrates subtle uptake in an enlarged right external node b which would be difficult to discern without knowledge of the CT findings. Below SUV max of 2. The lowest SUV max in nodes with malignant cytology was 3. There may be a role for other radiotracers such as fluorothymidine FLT or amino acid substrates in this setting. The humerus has predominantly cortical bone and has a lower level of bone metabolism compared to lumbar spine which is rich in trabecular bone [21]. Initial workup with endoscopic ultrasound and biopsy of the subcarinal node was non-diagnostic with necrotic tissue. Sheikh takes us through the basics and shares valuable tips on the importance of getting a second opinion on your FDG PET scan.

The standardized uptake value SUV is a nuclear medicine term, used in positron emission tomography PET as well as in modern calibrated single photon emission tomography SPECT imaging for a semiquantitative analysis.

Nucl Med Commun. Cancer Imaging 16 , 35 Cancer Imaging. Under fasting conditions, glucose and its analogue, FDG, have facilitated uptake into the liver and therefore generally this organ has significantly higher activity than the blood. In malignancies with a range of well- to poorly-differentiated phenotypes particularly endocrine tumours , it is possible to visualise tumour heterogeneity with different grades of disease at varying sites. Get a second opinion today. Sign Up. Immediately after and without moving the patient, an emission scan was obtained in 3D mode in 11 beds at 3 minutes per bed over the same anatomical regions. Log in Sign up. J Clin Densitom 10 : 46— Nucl Med Biol.