Lupron wiki

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Leuprorelin , also known as leuprolide , is a manufactured version of a hormone used to treat prostate cancer , breast cancer , endometriosis , uterine fibroids , as part of transgender hormone therapy , for early puberty , or to perform chemical castration of violent sex offenders. Leuprorelin is in the gonadotropin-releasing hormone GnRH analogue family of medications. Leuprorelin was patented in and approved for medical use in the United States in Leuprorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer and breast cancer. It may also be used for estrogen-dependent conditions such as endometriosis [12] or uterine fibroids. It may be used for precocious puberty in both males and females, [13] and to prevent premature ovulation in cycles of controlled ovarian stimulation for in vitro fertilization IVF. This use is controversial since the Lupron label advises against using the drug when one is considering pregnancy, due to a risk of birth defects.

Lupron wiki

Language Label Description Also known as English leuprolide. PubChem CID. Leuprorelin English. Lupron Depot. World Health Organisation international non-proprietary name. Leuprolide English. Food and Drug Administration. Inxight: Drugs Database. Gonadotropin releasing hormone receptor. Guide to Pharmacology Ligand ID. LiverTox likelihood score. LiverTox toxicity likelihood category E.

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Leuprorelin , also known as leuprolide , is a manufactured version of a hormone used to treat prostate cancer , breast cancer , endometriosis , uterine fibroids , as part of transgender hormone therapy , for early puberty , or to perform chemical castration of violent sex offenders. Leuprorelin is in the gonadotropin-releasing hormone GnRH analogue family of medications. Leuprorelin was patented in and approved for medical use in the United States in Leuprorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer and breast cancer. It may also be used for estrogen-dependent conditions such as endometriosis [12] or uterine fibroids.

It helps to slow down testosterone production, which plays a role in the growth of prostate cancer cells. Lupron is a brand name for leuprolide acetate, a luteinizing hormone-releasing hormone LHRH agonist. LHRH is a naturally occurring hormone that stimulates the production of testosterone in the testes. Lupron effectively blocks LHRH, so it reduces the amount of testosterone in your body. Lupron is a type of hormone therapy used to treat prostate cancer, which is powered by testosterone. Male hormones give prostate cancer cells the fuel they need to grow and spread. The goal of hormone treatments, such as Lupron, is to deprive cancer cells of this fuel to slow disease progression. That said, Lupron is not a cure for prostate cancer. Rather, it works to slow down the growth and spread of the cancer. For some men, Lupron initially slows down progression, but then the cancer becomes resistant and stops responding to treatment.

Lupron wiki

Leuprorelin , also known as leuprolide , is a manufactured version of a hormone used to treat prostate cancer , breast cancer , endometriosis , uterine fibroids , as part of transgender hormone therapy , for early puberty , or to perform chemical castration of violent sex offenders. Leuprorelin is in the gonadotropin-releasing hormone GnRH analogue family of medications. Leuprorelin was patented in and approved for medical use in the United States in Leuprorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer and breast cancer. It may also be used for estrogen-dependent conditions such as endometriosis [12] or uterine fibroids. It may be used for precocious puberty in both males and females, [13] and to prevent premature ovulation in cycles of controlled ovarian stimulation for in vitro fertilization IVF. This use is controversial since the Lupron label advises against using the drug when one is considering pregnancy, due to a risk of birth defects. It may be used to reduce the risk of premature ovarian failure in women receiving cyclophosphamide for chemotherapy. Along with triptorelin and goserelin , it has been used to delay puberty in transgender youth until they are old enough to begin hormone replacement therapy. This use of the drug is off-label, however, not having been approved by the Food and Drug Administration and without data on long-term effects of this use.

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Agonists: Peptides: Choriogonadotropin alfa Human chorionic gonadotropin Luteinizing hormone Lutropin alfa Menotropin human menopausal gonadotropin. World Health Organization model list of essential medicines: 21st list Along with triptorelin and goserelin , it has been used to delay puberty in transgender youth until they are old enough to begin hormone replacement therapy. Please read our full disclaimer here. Precautions with Alcohol. The risk appears low based on the reported odds ratios, and should be evaluated carefully along with cardiovascular risk factors when determining a treatment for patients with prostate cancer. In October , the US Department of Justice, states attorneys general, and TAP Pharmaceutical Products, a subsidiary of Abbott Laboratories, settled criminal and civil charges against TAP related to federal and state medicare fraud and illegal marketing of the drug leuprorelin. Leuprorelin was discovered and first patented in and was introduced for medical use in It is considered a possible treatment for paraphilias. Language Label Description Also known as English leuprolide. Since , the FDA has been evaluating leuprorelin's connection to pain and discomfort in musculoskeletal and connective tissue. Brand Names. During the clinical trials, injection sites were closely monitored. Archived PDF from the original on 10 April

Lupron is a drug doctors prescribe to treat prostate cancer.

If this drug is used during pregnancy , or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus. This protracted downregulation of GnRH receptor activity is the targeted objective of leuprorelin therapy and ultimately results in decreased LH and FSH secretion, leading to hypogonadism and thus a dramatic reduction in estradiol and testosterone levels regardless of sex. Retrieved 11 August This use is controversial since the Lupron label advises against using the drug when one is considering pregnancy, due to a risk of birth defects. Retrieved 21 June There have since been various suits concerning leuprorelin use, none successful. UniChem compound ID. It is considered a possible treatment for paraphilias. Between and , the FDA updated the Lupron drug label to include new safety information on the risk of thromboembolism, loss of bone density and convulsions. Namespaces Home Page Discussion. Wiktionary 0 entries edit. No patient discontinued therapy due to an injection site adverse event.