Gonapeptyl kullananlar

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Gonapeptyl kullananlar

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Sulinex Gleitgelen Jel.

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It is used to treat prostate cancer. It can be given alone or with radiotherapy or surgery. It is best to read this information with our general information about hormonal therapies and the type of cancer you have. Your doctor will talk to you about this treatment and its possible side effects before you agree consent to have treatment. Triptorelin can also be used to treat breast cancer. This information is correct at time of publishing. But sometimes the types of cancer this treatment is used for, or treatment side effects, may change between revision dates.

Gonapeptyl kullananlar

Gonapeptyl is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone LHRH. Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. The first administration of triptorelin is followed by a transient surge of follicle stimulating hormone FSH , luteinizing hormone LH , estradiol,and testosterone. The time, peak and decline of testosterone in the body varies depending on the dose administered. This initial surge is often responsible for worsening of prostate cancer symptoms such as urethral or bladder outlet obstruction, bone pain, spinal cord injury and hematuria in the early stages. A sustained decrease in FSH and LH, and significant reduction of testicular steroidogenesis is usually seen weeks post-initiation of therapy. This result is a reduction of serum testosterone to levels which are typically seen in surgically castrated men.

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Gonapeptyl depot injection contains the active ingredient triptorelin acetate, which is a type of medicine known as a gonadorelin LHRH analogue.

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