Glove and stocking pattern

The peripheral nerves consist of bundles of long neuronal axons as they exit the central nervous system CNS. Some peripheral nerves are wrapped in a myelin sheath generated by Schwann cells, whereas others are unmyelinated. Peripheral nerves serve different motor, glove and stocking pattern, sensory, and autonomic functions. The term peripheral neuropathy is usually used to describe symmetric and universal damage to adjacent nerves.

Many patients presenting themselves with complaints of numbness or weakness will eventually be shown to have a disorder of the peripheral nervous system. Although the differential diagnosis is large in these disorders, the combination of a directed neurologic history exam along with relatively simple ancillary testing will quickly narrow the differential diagnosis. As many of these disorders are treatable or curable, prompt recognition, especially early in the clinical course, is important. Peripheral neuropathies a. Many disease processes may preferentially attack either the axon or the myelin sheath of the peripheral nerve.

Glove and stocking pattern

Stocking glove neuropathy refers to symptoms of peripheral neuropathy that cause numbness, weakness, or sensory changes in the hands and feet. It has a number of potential causes, including diabetes. Peripheral neuropathy is nerve damage to the peripheral nerves. These nerves send signals throughout the body and to the brain and spinal cord , also known as the central nervous system. Some types of peripheral neuropathy start in the hands and feet. Doctors call this stocking and glove distribution, as people may feel as though they are wearing stockings and gloves when they are not. This article explains what stocking glove neuropathy is, its symptoms, causes, and treatment options. It also lists some potential prevention methods. Stocking and glove distribution refers to a specific symptom people may experience with peripheral neuropathy. Peripheral neuropathy occurs due to damage to the motor, sensory, or autonomic nerves.

In addition to causing unremitting pain, DPN is also associated with increased mortality. Clinicians generally start with monotherapy with duloxetine and pregabalin drugs of choicebut progress to combination therapies.

In the Western world, diabetes is the biggest cause of peripheral neuropathy, usually distal symmetric polyneuropathy but some times another polyneuropathy or a focal neuropathy. In addition, hypothyroidism and acromegaly can cause carpal tunnel syndrome and other sensory complaints. A complete blood cell count, nerve-conduction tests, thyroid-function tests needed in all patients with carpal tunnel syndrome , and when necessary, needle electromyography can help confirm the diagnosis. Treatment of underlying disease is the most successful management approach: Tight glucose control in diabetic patients, thyroid hormone replacement therapy in patients with hypothyroidism, and removal of the pituitary adenoma in patients with acromegaly are of proven benefit. Significant symptomatic relief of dysesthesias can be obtained with use of capsaicin cream, tricyclic antidepresants, anticonvulsant agents, or an antiarrhythmic drug. Abstract In the Western world, diabetes is the biggest cause of peripheral neuropathy, usually distal symmetric polyneuropathy but some times another polyneuropathy or a focal neuropathy.

Peripheral neuropathy is one of the most common neurologic problems encountered by family physicians. It is important to differentiate peripheral neuropathy from other disorders with similar presentations and to identify and address potential causes. The pathophysiology of peripheral neuropathy results from injury to small- or large-diameter nerve fibers. Damage can occur to the cell body, axon, myelin sheath, or a combination of these, leading to symptoms such as numbness, tingling, pain, and weakness. Small nerve fibers mediate pain, temperature, and autonomic functions. A systematic approach should be used to evaluate and manage patients with symptoms of peripheral neuropathy Figure 1.

Glove and stocking pattern

Stocking glove neuropathy refers to symptoms of peripheral neuropathy that cause numbness, weakness, or sensory changes in the hands and feet. It has a number of potential causes, including diabetes. Peripheral neuropathy is nerve damage to the peripheral nerves.

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About Us. On nerve conduction studies, demyelination is associated with markedly markedly slowed conduction velocities and conduction block between distal and proximal stimulation sites. Acute Care. Several medical conditions are highly associated with peripheral neuropathy. Treatment for stocking glove neuropathy may depend on the underlying cause and extent of nerve damage. Clinical Clues to an Inherited Peripheral Neuropathies. The data follow the FDA approval of omalizumab for the reduction of allergic reactions, including anaphylaxis, that can occur after exposure to 1 or more foods. The National Institute of Neurological Disorders and Stroke notes that symptoms may develop over time, from days to weeks or even years. Symptoms and Signs When nerve is diseased, it can react in a limited number of ways. Mayo Clin Proc. The damage and clinical manifestations are usually located distally with a proximal progression. As many of these disorders are treatable or curable, prompt recognition, especially early in the clinical course, is important. Diabetes can cause nerve damage in the hands and feet. Electrodiagnostic studies are recommended if the diagnosis remains unclear after initial diagnostic testing and a careful history and physical examination.

Half of people who have diabetes eventually develop diabetic peripheral neuropathy, and the warning signs are sensory symptoms that start in the distant periphery and progressing in a characteristic 'glove and stocking' way. People who have diabetes fear diabetic peripheral neuropathy DPN , as it is common and the chance of developing this painful condition increases as disease duration increases. Half of people who have diabetes eventually develop DPN, and the warning signs are sensory symptoms that start in the distant periphery and progressing in a characteristic 'glove and stocking' way.

Winer JB. Am J Manag Care. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Sensory loss to vibration and proprioception Ataxia Clumsiness Areflexia Hypotonia. Acute inflammatory neuropathies require more urgent and aggressive management with intravenous immunoglobulin 9 or plasmaphereis. Creating these plans is often difficult. What it is Symptoms Causes Treatment Diagnosis Prevention Outlook Summary Stocking glove neuropathy refers to symptoms of peripheral neuropathy that cause numbness, weakness, or sensory changes in the hands and feet. Medically reviewed by Kerry Boyle D. In some cases , stocking glove neuropathy may ease if a person works with a doctor to treat the underlying cause. Small nerve fiber damage may constitute the earliest stages of some peripheral neuropathies and cannot be detected by electrodiagnostic studies. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Clinical Clues to an Inherited Peripheral Neuropathies. The bottom-line message from this review is that all clinicians need to watch for DPN in their diabetic patients, and treat early. Significant symptomatic relief of dysesthesias can be obtained with use of capsaicin cream, tricyclic antidepresants, anticonvulsant agents, or an antiarrhythmic drug. Can foot massages help with diabetic neuropathy?