Can i take glimepiride at night

Carefully follow the special meal plan your doctor gave you. This is a very important part of controlling your condition, and is necessary if the medicine is to work properly.

Remember to follow any advice you have been given about what you should or shouldn't eat, and try to take some regular exercise. Side-effects are rare, but make sure you know how to recognise the symptoms of low blood sugar glucose. These include feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding palpitations , and feeling dizzy. Insulin is a hormone which is made naturally in your body, in the pancreas. It helps to control the levels of sugar glucose in your blood.

Can i take glimepiride at night

Federal government websites often end in. The site is secure. Additionally, is has been shown to work via several extra pancreatic mechanisms. It is administered as monotherapy in patients with type 2 diabetes mellitus in whom glycemic control is not achieved by dietary and lifestyle modifications. It can also be combined with other antihyperglycemic agents, including metformin and insulin, in patients who are not adequately controlled by sulfonylureas alone. In clinical studies, glimepiride was generally associated with lower risk of hypoglycemia and less weight gain compared to other sulfonylureas. Glimepiride use may be safer in patients with cardiovascular disease because of its lack of detrimental effects on ischemic preconditioning. It is effective in reducing fasting plasma glucose, post-prandial glucose, and glycosylated hemoglobin levels and is a useful, cost-effective treatment option for managing type 2 diabetes mellitus. Diabetes is a major public health problem affecting million people worldwide. Insulin resistance is a complex phenomenon exacerbated by obesity, particularly central obesity, and is believed to start at a young age because hyperinsulinemia is observed in preteens when both parents have diabetes. Management of hyperglycemia in type 2 diabetes: a patient-centered approach.

Brit J Diab Vas Dis. Curr Med Res Opin. Forty-five clinical trials were used to describe the clinical efficacy and safety of glimepiride.

Back to Glimepiride. Doses of glimepiride can vary. Follow your doctor's instructions when taking this medicine. Your doctor will tell you how many tablets to take. You may need to take 1 or 2 tablets to make up your daily dose. The usual starting dose for adults is 1mg, taken once a day.

Glimepiride is available as the brand-name drug Amaryl and as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version. This drug may be used as part of a combination therapy. That means you need to take it with other drugs.

Can i take glimepiride at night

Remember to follow any advice you have been given about what you should or shouldn't eat, and try to take some regular exercise. Side-effects are rare, but make sure you know how to recognise the symptoms of low blood sugar glucose. These include feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding palpitations , and feeling dizzy. Insulin is a hormone which is made naturally in your body, in the pancreas. It helps to control the levels of sugar glucose in your blood.

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Sulfonylureas SUs are widely used in the management of T2DM as insulin secretagogues and are named for their common core configuration. Glimepiride side-effects What can I do if I experience this? However, Glimepiride can cause low blood sugar and weight gain. Get the Mayo Clinic app. What are the uses of Glimepiride? Similar significant reduction in FPG and HbA 1c in both groups; significantly lower C peptide and fasting insulin concentrations with G than with glyburide. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. A dose response study of glimepiride in patients with NIDDM who have previously received sulfonylurea agents. Rosenstock J, Fitchet M. Metabolic and adipose risk factors for NIDDM and coronary disease in third-generation Japanese-American men and women with impaired glucose tolerance. Conclusion Glimepiride is a second-generation sulfonylurea which can be used as monotherapy or in combination with other antihyperglycemic agents, including insulin. The goals of pharmacologic therapy in diabetes are to achieve good glycemic control while avoiding hypoglycemia and weight gain so as to decrease the risk of future micro- and macrovascular complications.

Back to Glimepiride.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. Rosenstock J, Fitchet M. If you stop taking it suddenly, your diabetes may get worse. Results of a randomized, double-blind, placebo-controlled study administering glimepiride to patients with type 2 diabetes mellitus inadequately controlled with rosiglitazone monotherapy. This is because good control of blood sugar levels reduces the risk of complications later on. Data from animal studies were also included if human data were not available. The study concluded that the risk for nocturnal hypoglycemia was lower with glimepiride in combination with morning and bedtime insulin glargine than with glimepiride in combination with bedtime NPH insulin. Second-generation SUs include glyburide glibenclamide , glipizide, gliquidone, and glimepiride, which vary in duration of action. Glimepiride pharmacokinetics in obese versus non-obese diabetic patients. Footnotes Disclosure The authors have no conflicts of interest to declare. Significantly reduced exogenous insulin requirement with G compared with P. Shah encourages individuals to start with anaerobic exercises and then transition to aerobic exercises. Do not keep out-of-date or unwanted medicines. Though you can exercise at any time of the day, Dr. In a study involving patients with poorly controlled T2DM, glimepiride was added to metformin monotherapy.