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This photo provided by the Osage County, Kan.

Dennis Lynn Rader born March 9, , also known as BTK an abbreviation he gave himself, for " bind, torture, kill " , is an American serial killer who murdered at least ten people in Wichita and Park City, Kansas , between and Although Rader occasionally killed or attempted to kill men and children, he typically targeted women. His victims were often bound, sometimes with objects from their homes, and either suffocated with a plastic bag or manually strangled with a ligature. In addition, Rader stole keepsakes from his female victims, including underwear, licenses, and personal items. He often sent taunting letters to police and media outlets describing the details of his crimes. He is currently serving ten consecutive life sentences at the El Dorado Correctional Facility.

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The sheriff's office, which recently dug up the former property of Rader in Park City, Kan. According to The Associated Press , Garber, 22, was raped and strangled to death in Her body remained unidentified until Sheriff Eddie Virden visited the Kansas prison where Rader is currently serving multiple life sentences, according to 12 News. He told the outlet the convicted killer spoke to him about his life — starting at age three — and the events leading up to him being in prison, including his 10 murders in the Wichita area. Want to keep up with the latest crime coverage? And we didn't want to rule him out, and we're still not ruling him out. Use limited data to select advertising. Create profiles for personalised advertising. Use profiles to select personalised advertising. Create profiles to personalise content. Use profiles to select personalised content. Measure advertising performance. Measure content performance. Understand audiences through statistics or combinations of data from different sources.

Retrieved January 21,

We may earn commission from links on this page, but we only recommend products we back. This August, an Oklahoma sheriff identified convicted murderer Dennis Rader as the prime suspect in the disappearance of year-old Cynthia Kinney from Pawhuska, Oklahoma. But in a letter from prison to a Tulsa television reporter, the infamous BTK Killer who murdered 10 people writes he has nothing to do with the unsolved case. Rader vehemently denies he killed Kinney in the letter that was shared during a televised segment on October 12 and claims any details that might tie him to the case are coincidental. Living a double life as a devoted family and company man by day, Rader brutally murdered 10 people—with his nickname representing his method of binding, torturing, and killing victims. He also taunted authorities through brazen correspondence with local news outlets.

BTK contains five different protein interaction domains. BTK plays a crucial role in B cell development as it is required for transmitting signals from the pre-B cell receptor that forms after successful immunoglobulin heavy chain rearrangement. PIP3 binding induces Btk to phosphorylate phospholipase C , which in turn hydrolyzes PIP 2 , a phosphatidylinositol , into two second messengers, inositol triphosphate IP3 and diacylglycerol DAG , which then go on to modulate the activity of downstream proteins during B-cell signalling. Mutations in the BTK gene are implicated in the primary immunodeficiency disease X-linked agammaglobulinemia Bruton's agammaglobulinemia ; sometimes abbreviated to XLA and selective IgM deficiency. The Btk gene is located on the X chromosome Xq Of these, at least are considered to be disease-causing mutations. Various drugs that inhibit BTK are in clinical trials: [19]. Bruton's tyrosine kinase was discovered in and is named for Ogden Bruton , who first described XLA in

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We may earn commission from links on this page, but we only recommend products we back. A family man, government worker, and church leader by day, Rader was smart enough to blend into his community and avoid detection for the string of victim stalking and killings that fulfilled his sexual desires. And while he relished the headlines that announced his grotesque acts and the taunting messages he relayed to the media, he also controlled his impulses enough to suddenly stop the killings and disappear before authorities could get too close to his trail. Yet it was his insatiable lust for attention that ultimately proved to be his Achilles heel. BTK reemerged years later to remind police that he remained at large but got too careless with his cat-and-mouse games, providing investigators with an opening to crack the once-unsolvable case and bring the killer to justice. Now close to two decades later, Rader is back in the headlines. He compared himself to the Gilgo Beach murder suspect earlier this summer. Moreover, authorities have named him a prime suspect in two unsolved disappearances and possibly identified a 11 th BTK victim. A year-old married Air Force veteran, Rader makes the plunge into infamy after severing a phone line and entering the East Wichita home of Joseph and Julie Otero, the latter a former coworker at the Coleman equipment company.

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After exhaustive investigations, none of these agencies discovered any further murders attributable to Rader, supporting early suspicions that Rader would have taken responsibility for any additional murders that he had committed. Both parents worked long hours and paid little attention to their children at home; Rader later described feeling ignored by his mother in particular and resenting her for it. Archived from the original on July 24, Gary Ridgway. Tyler Piccotti joined the Biography. July 16, Rader talked about innocuous topics such as the weather during the minute drive to El Dorado, but began to cry when the victims' families' statements from the court proceedings came on the radio. Fact Check. On September 16, , Rader strangled year-old Vicki Lynn Wegerle to death with a nylon stocking at her house in Wichita. Retrieved October 17, — via Kansas. Archived from the original on May 27, Kate, Princess of Wales, photo. September 2, An autopsy revealed she had been raped, strangled and restrained with different bindings about two months before her body was found.

We may earn commission from links on this page, but we only recommend products we back. This August, an Oklahoma sheriff identified convicted murderer Dennis Rader as the prime suspect in the disappearance of year-old Cynthia Kinney from Pawhuska, Oklahoma.

Then, Rader initiated a series of eleven communications to the local media. Retrieved June 9, Our staff also works with freelance writers, researchers, and other contributors to produce the smart, compelling profiles and articles you see on our site. Although Rader occasionally killed or attempted to kill men and children, he typically targeted women. The former Air Force sergeant had lived in the Wichita area almost his entire life, earning a criminal justice degree at a local university. CBS News. BTK terrorized Wichita, Kansas, from until he was finally caught 30 years later. The Witchita Eagle. They do not feel the effects of others' fear, sadness, or pain, so they have to work to interpret their environment. Standing in court before the judge, the victims' families, and the assembled press, Rader listened as the judge read out the details of his offenses.