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This medicine is known as sertraline. Exercise has many benefits for older adults and can help you to live a longer and healthier life.

Go PRO to access past versions. Pregnancy Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants during pregnancy. Risk Summary Based on data from published observational studies, exposure to SSRIs, particularly in the month before delivery, has been associated with less than 2-fold increase in the risk of postpartum hemorrhage [see Warnings and Precautions 5. Overall, available published epidemiologic studies of pregnant women exposed to sertraline in the first trimester suggest no difference in major birth defect risk compared to the background rate for major birth defects in comparator populations. Some studies have reported increases for specific major birth defects; however, these study results are inconclusive [See Data].

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If you are a consumer or patient please visit this version. Antidepressants increased the risk compared to placebo of suicidal thinking and behavior suicidality in children, adolescents, and young adults in short-term studies of major depressive disorder MDD and other psychiatric disorders. Anyone considering the use of Sertraline Hydrochloride Tablets or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Sertraline Hydrochloride Tablets are not approved for the treatment of major depressive disorder in pediatric patients. Sertraline is a selective serotonin reuptake inhibitor SSRI for oral administration. It has a molecular weight of Sertraline hydrochloride has the following chemical name: 1S-cis 3,4-dichlorophenyl -1,2,3,4-tetrahydro-N-methylnaphthalenamine hydrochloride. Sertraline hydrochloride is a white crystalline powder that is slightly soluble in water and isopropyl alcohol, and sparingly soluble in ethanol. The mechanism of action of sertraline is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin 5HT.

Ensure an adequate airway, oxygenation and ventilation. The antidepressant action of sertraline hydrochloride in hospitalized depressed patients has not been adequately studied. Higher plasma levels in the year old group were largely attributable to patients with lower body weights, blue oval pill 213.

If you are a consumer or patient please visit this version. Antidepressants increased the risk compared to placebo of suicidal thinking and behavior suicidality in children, adolescents, and young adults in short-term studies of major depressive disorder MDD and other psychiatric disorders. Anyone considering the use of Sertraline hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide.

This medicine is known as sertraline. Exercise has many benefits for older adults and can help you to live a longer and healthier life. Here are 6 benefits of exercise for older adults and seniors. Exercise has many benefits on physical and mental health wellbeing. A few minutes of physical activity a day can have a positive impact on your mood. Bipolar disorder is a type of mood disorder. People with bipolar disorder fluctuate from feeling down and depressed to feeling super-charged or manic. Body dysmorphic disorder BDD is a type of anxiety disorder where people become preoccupied with perceived defects or flaws in their appearance. Facebook Twitter Email Print. Top 6 benefits of exercise for older adults Exercise has many benefits for older adults and can help you to live a longer and healthier life.

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Go PRO to access past versions. Prescribers or other health professionals should inform patients, their families, and their caregivers about the benefits and risks associated with treatment with sertraline hydrochloride and should counsel them in its appropriate use. The prescriber or health professional should instruct patients, their families, and their caregivers to read the Medication Guide and should assist them in understanding its contents. Patients should be given the opportunity to discuss the contents of the Medication Guide and to obtain answers to any questions they may have. The complete text of the Medication Guide is reprinted at the end of this document. Patients should be advised of the following issues and asked to alert their prescriber if these occur while taking sertraline hydrochloride. Clinical Worsening and Suicide Risk: Patients, their families, and their caregivers should be encouraged to be alert to the emergence of anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia psychomotor restlessness , hypomania, mania, other unusual changes in behavior, worsening of depression, and suicidal ideation, especially early during antidepressant treatment and when the dose is adjusted up or down.

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In particular, some evidence suggests that selective serotonin reuptake inhibitors SSRIs can cause such untoward sexual experiences. If you take too many sertraline tablets, call your healthcare provider or poison control center right away, or go to the nearest hospital emergency room right away. Discontinuation Syndrome Advise patients not to abruptly discontinue sertraline and to discuss any tapering regimen with their healthcare provider. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Accordingly, estimates of the incidence of untoward sexual experience and performance cited in product labeling, are likely to underestimate their actual incidence. Pup body weights were also decreased during the first four days after birth. The pooled analyses of placebo-controlled trials in children and adolescents with MDD, obsessive compulsive disorder OCD , or other psychiatric disorders included a total of 24 short-term trials of 9 antidepressant drugs in over patients. Dosage for Hepatically Impaired Patients The use of sertraline in patients with liver disease should be approached with caution. Serotonin release by platelets plays an important role in hemostasis. General information about the safe and effective use of sertraline tablets. Other Serotonergic Drugs. Who should not take sertraline tablets?

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There were subjects in placebo-controlled geriatric clinical studies of Sertraline hydrochloride in major depressive disorder. Switching Patients to or from a Monoamine Oxidase Inhibitor At least 14 days should elapse between discontinuation of an MAOI and initiation of therapy with sertraline hydrochloride. Ejaculation failure 1. What is the most important information I should know about Sertraline hydrochloride? Accordingly, prothrombin time should be carefully monitored when sertraline hydrochloride therapy is initiated or stopped. At baseline the mean weight for adolescents was Sertraline tablets, USP for oral administration are supplied as scored tablets containing An event was considered treatment-emergent if it occurred for the first time or worsened while receiving therapy following baseline evaluation. Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide. Talk to your healthcare provider if you do not think that your condition is getting better with sertraline tablets treatment. Sertraline hydrochloride tablets are not approved for the treatment of major depressive disorder in pediatric patients. Post hoc exploratory analyses revealed a significant difference between Sertraline hydrochloride and placebo on the CAPS, IES and CGI in women, regardless of baseline diagnosis of comorbid major depressive disorder, but essentially no effect in the relatively smaller number of men in these studies.